Health Information

Symptoms of Chronic Kidney Disease

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In its early phases, chronic kidney disease usually doesn’t cause symptoms. However, as the condition progresses to the end-stage renal disease stage, it can cause a number of symptoms, including:

  • Feeling weak or tired
  • Trouble sleeping
  • Swelling of feet and ankles
  • Poor appetite
  • Needing to urinate more often, especially at night
  • Muscle cramping at night
  • Nausea
  • Itching
  • Shortness of breath
  • Metallic taste in mouth
  • Chest pain
  • Confusion
  • Hiccups
  • Irritability
  • Difficulty concentrating
  • Reduced interest in sex
  • Menstrual irregularities
  • Numbness and tingling in hands and feet

Revision Information

  • Are you at increased risk for chronic kidney disease? National Kidney Foundation website. Available at: http://www.kidney.org/atoz/pdf/11-10-1814.pdf. Published 2010. Accessed July 2, 2013.

  • Chronic kidney disease. EBSCO DynaMed website. Available at: https://dynamed.ebscohost.com/about/about-us. Updated April 22, 2013. Accessed July 2, 2013.

  • Chronic kidney disease: patient information handout. American Academy of Family Physicians website. Available at: http://familydoctor.org/online/famdocen/home/common/kidney/832.html. Updated November 2010. Accessed July 2, 2013.

  • National Kidney Foundation. Kidney Disease Outcomes Quality Initiative (K/DOQI) clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification. Am J Kidney Dis. 2002;39:S1-266.

  • Snyder S, Pendergraph B. Detection and evaluation of chronic kidney disease. Am Fam Physicians. 2005;72:723-732.